Research in IMO
Ongoing projects
Identification of new retinal dystrophies genes and characterization of genotype-phenotype correlations
The aim of this research project is to identify new causative genes of retinal dystrophies, in order to contribute to the knowledge and diagnosis of these diseases.
XPLORE
A Phase III Double-Blind, Parallel Group, Multicenter Study to Compare the Efficacy and Safety of Xlucane versus Lucentis in Patients with Neovascular Age-Related Macular Degeneration
ENDOART
Prospective, feasibility study to evatuate the safety of the EndoArt for treatment of subjects suffering from corneal edema.
Project history
Mass sequencing of exomes for the identification of new genes and variants responsible for retinal dystrophies
Retinitis pigmentosa, with a prevalence of 1 in 4,000 people and more than one million sufferers worldwide, is the most common retinal dystrophy. These diseases are neurodegenerative and caused by the death of the photoreceptors and cells of the retinal pigment epithelium.
Azure
Randomised, active-controlled, parallel group, phase III trial on the efficacy, safety and tolerability of 2 mg aflibercept administered with intyravidial injections using two different regimens of treatment for subjects with neovascular age-related macular degeneration.